Pulsing or daily administration?

The optimal dosing regimen for oral transfer factor supplements remains unclear. Many clinicians have found that pulsing treatments with other immune boosting supplements and drugs, like Immunovir (Isoprinosine), is more effective than daily dosing. The concern is that the immune system will learn to ignore a consistent signal. As such, they recommend pulsing the treatments in some sort of staggered regimen with breaks in between. For instance, rather than daily dosing, as the maker of Immunovir (Newport Pharmaceuticals) recommends, Dr. Paul Cheney, a CFIDS specialist, recommends a pattern in which 6 pills are taken Monday-Friday during week one, 2 pills per day Monday-Friday during week two. No pills on the weekends. Take every other month off.

Presently, companies manufacturing products that contain transfer factors recommend daily dosing. It is unclear whether a pulsing strategy would be more effective.